  {"id":1548,"date":"2019-06-14T20:06:32","date_gmt":"2019-06-15T01:06:32","guid":{"rendered":"https:\/\/www.vanderbilt.edu\/csb\/?page_id=1548"},"modified":"2023-09-25T11:37:24","modified_gmt":"2023-09-25T16:37:24","slug":"ivdr","status":"publish","type":"page","link":"https:\/\/www.vanderbilt.edu\/csb\/facilities\/biomolecular-nmr\/ivdr\/","title":{"rendered":"InVitro Diagnostics Research (IVDr)"},"content":{"rendered":"<h3>Metabolomics by Nuclear Magnetics Resonance (NMR)<\/h3>\n<figure id=\"attachment_1856\" aria-describedby=\"caption-attachment-1856\" style=\"width: 224px\" class=\"wp-caption alignright\"><img data-attachment-id=\"1856\" data-permalink=\"https:\/\/www.vanderbilt.edu\/csb\/facilities\/biomolecular-nmr\/ivdr\/samplejet\/\" data-orig-file=\"https:\/\/cdn.vanderbilt.edu\/vu-URL\/wp-content\/uploads\/sites\/212\/2019\/09\/19171456\/SampleJet.jpg\" data-orig-size=\"1920,2576\" data-comments-opened=\"1\" data-image-meta=\"{&quot;aperture&quot;:&quot;2.8&quot;,&quot;credit&quot;:&quot;&quot;,&quot;camera&quot;:&quot;Photosmart M425&quot;,&quot;caption&quot;:&quot;&quot;,&quot;created_timestamp&quot;:&quot;1260798373&quot;,&quot;copyright&quot;:&quot;&quot;,&quot;focal_length&quot;:&quot;6&quot;,&quot;iso&quot;:&quot;200&quot;,&quot;shutter_speed&quot;:&quot;0.016667000140059&quot;,&quot;title&quot;:&quot;&quot;,&quot;orientation&quot;:&quot;1&quot;}\" data-image-title=\"SampleJet\" data-image-description=\"\" data-image-caption=\"\" data-medium-file=\"https:\/\/cdn.vanderbilt.edu\/vu-URL\/wp-content\/uploads\/sites\/212\/2019\/09\/19171456\/SampleJet-224x300.jpg\" data-large-file=\"https:\/\/cdn.vanderbilt.edu\/vu-URL\/wp-content\/uploads\/sites\/212\/2019\/09\/19171456\/SampleJet-763x1024.jpg\" loading=\"lazy\" class=\"wp-image-1856 size-medium\" src=\"https:\/\/cdn.vanderbilt.edu\/vu-URL\/wp-content\/uploads\/sites\/212\/2019\/09\/19171456\/SampleJet-224x300.jpg\" alt=\"\" width=\"224\" height=\"300\" srcset=\"https:\/\/cdn.vanderbilt.edu\/vu-URL\/wp-content\/uploads\/sites\/212\/2019\/09\/19171456\/SampleJet-224x300.jpg 224w, https:\/\/cdn.vanderbilt.edu\/vu-URL\/wp-content\/uploads\/sites\/212\/2019\/09\/19171456\/SampleJet-768x1030.jpg 768w, https:\/\/cdn.vanderbilt.edu\/vu-URL\/wp-content\/uploads\/sites\/212\/2019\/09\/19171456\/SampleJet-763x1024.jpg 763w, https:\/\/cdn.vanderbilt.edu\/vu-URL\/wp-content\/uploads\/sites\/212\/2019\/09\/19171456\/SampleJet-108x144.jpg 108w, https:\/\/cdn.vanderbilt.edu\/vu-URL\/wp-content\/uploads\/sites\/212\/2019\/09\/19171456\/SampleJet-142x190.jpg 142w, https:\/\/cdn.vanderbilt.edu\/vu-URL\/wp-content\/uploads\/sites\/212\/2019\/09\/19171456\/SampleJet.jpg 1920w\" sizes=\"(max-width: 224px) 100vw, 224px\" \/><figcaption id=\"caption-attachment-1856\" class=\"wp-caption-text\">Sample robot holding five cartridges with 96 samples each<\/figcaption><\/figure>\n<p>The power of personalized genomic information has drawn mainstream media attention with services like Ancestry.com and 23andme.com. The field of personalized medicine has adapted the exploitation of the human genome but is quickly expanding to include other perspectives such as the<span class=\"apple-converted-space\">\u00a0<\/span><span class=\"scayt-misspell-word\">proteome <\/span>and<span class=\"apple-converted-space\">\u00a0<\/span><span class=\"scayt-misspell-word\">metabolome<\/span>. There is rapidly expanding knowledge associated with the health effects that are related to changes to the<span class=\"apple-converted-space\">\u00a0<\/span><span class=\"scayt-misspell-word\">metabolome<\/span>.<\/p>\n<p>We are excited to be one of the first Universities in the US to provide this tool to researchers and clinicians at ÌìÃÀ´«Ã½¹ÙÍø and the medical research community. \u00a0Being able to get a metabolic\u00a0profile of body fluids without any extensive sample preparation within hours will not only help to detect signs of a disease early but also serve as an efficient and powerful tool to discover new indicators for health related issues.<\/p>\n<p>Main advantages of the NMR \u00a0based method are:<\/p>\n<ul>\n<li>quantitative metabolite description<\/li>\n<li>reproducible results<\/li>\n<li>simple and fast sample preparation<\/li>\n<li>fully automated measurement and data analysis in minutes<\/li>\n<li>non-destructive<\/li>\n<li>data can be re-analyzed any time as new metabolites are added to the database<\/li>\n<\/ul>\n<figure id=\"attachment_1855\" aria-describedby=\"caption-attachment-1855\" style=\"width: 300px\" class=\"wp-caption alignleft\"><img data-attachment-id=\"1855\" data-permalink=\"https:\/\/www.vanderbilt.edu\/csb\/facilities\/biomolecular-nmr\/ivdr\/96-well\/\" data-orig-file=\"https:\/\/cdn.vanderbilt.edu\/vu-URL\/wp-content\/uploads\/sites\/212\/2019\/09\/19171456\/96-Well.jpg\" data-orig-size=\"2448,2184\" data-comments-opened=\"1\" data-image-meta=\"{&quot;aperture&quot;:&quot;2.4&quot;,&quot;credit&quot;:&quot;&quot;,&quot;camera&quot;:&quot;iPhone 5&quot;,&quot;caption&quot;:&quot;&quot;,&quot;created_timestamp&quot;:&quot;1561548118&quot;,&quot;copyright&quot;:&quot;&quot;,&quot;focal_length&quot;:&quot;4.12&quot;,&quot;iso&quot;:&quot;320&quot;,&quot;shutter_speed&quot;:&quot;0.05&quot;,&quot;title&quot;:&quot;&quot;,&quot;orientation&quot;:&quot;1&quot;}\" data-image-title=\"96-Well\" data-image-description=\"\" data-image-caption=\"\" data-medium-file=\"https:\/\/cdn.vanderbilt.edu\/vu-URL\/wp-content\/uploads\/sites\/212\/2019\/09\/19171456\/96-Well-300x268.jpg\" data-large-file=\"https:\/\/cdn.vanderbilt.edu\/vu-URL\/wp-content\/uploads\/sites\/212\/2019\/09\/19171456\/96-Well-1024x914.jpg\" loading=\"lazy\" class=\"wp-image-1855 size-medium\" src=\"https:\/\/cdn.vanderbilt.edu\/vu-URL\/wp-content\/uploads\/sites\/212\/2019\/09\/19171456\/96-Well-300x268.jpg\" alt=\"\" width=\"300\" height=\"268\" srcset=\"https:\/\/cdn.vanderbilt.edu\/vu-URL\/wp-content\/uploads\/sites\/212\/2019\/09\/19171456\/96-Well-300x268.jpg 300w, https:\/\/cdn.vanderbilt.edu\/vu-URL\/wp-content\/uploads\/sites\/212\/2019\/09\/19171456\/96-Well-768x685.jpg 768w, https:\/\/cdn.vanderbilt.edu\/vu-URL\/wp-content\/uploads\/sites\/212\/2019\/09\/19171456\/96-Well-1024x914.jpg 1024w\" sizes=\"(max-width: 300px) 100vw, 300px\" \/><figcaption id=\"caption-attachment-1855\" class=\"wp-caption-text\">96 sample Cartridge of 5mm NMR tubes containing samples<\/figcaption><\/figure>\n<p>Examples of this powerful diagnostic tool have been described in the literature, especially in the areas of early detection of newborn diseases, diabetes, and cancer to name just a few.<\/p>\n<h4>For more information, please contact:<\/h4>\n<p>Markus Voehler, Ph.D. \u00a0\u00a0<a href=\"mailto:m.voehler@vanderbilt.edu\">m.voehler@vanderbilt.edu<\/a>\u00a0 office: (615) 322 1573<\/p>\n<p>Don Stec, Ph.D. \u00a0<a href=\"mailto:donald.f.stec@Vanderbilt.Edu\">donald.f.stec@Vanderbilt.Edu<\/a>\u00a0 office: (615) 322 6704<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Metabolomics by Nuclear Magnetics Resonance (NMR) The power of personalized genomic information has drawn mainstream media attention with services like Ancestry.com and 23andme.com. The field of personalized medicine has adapted the exploitation of the human genome but is quickly expanding to include other perspectives such as the\u00a0proteome and\u00a0metabolome. There is rapidly expanding knowledge associated with&#8230;<\/p>\n","protected":false},"author":2065,"featured_media":0,"parent":120,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"spay_email":""},"tags":[],"acf":[],"jetpack_sharing_enabled":true,"_links":{"self":[{"href":"https:\/\/www.vanderbilt.edu\/csb\/wp-json\/wp\/v2\/pages\/1548"}],"collection":[{"href":"https:\/\/www.vanderbilt.edu\/csb\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/www.vanderbilt.edu\/csb\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/www.vanderbilt.edu\/csb\/wp-json\/wp\/v2\/users\/2065"}],"replies":[{"embeddable":true,"href":"https:\/\/www.vanderbilt.edu\/csb\/wp-json\/wp\/v2\/comments?post=1548"}],"version-history":[{"count":18,"href":"https:\/\/www.vanderbilt.edu\/csb\/wp-json\/wp\/v2\/pages\/1548\/revisions"}],"predecessor-version":[{"id":4882,"href":"https:\/\/www.vanderbilt.edu\/csb\/wp-json\/wp\/v2\/pages\/1548\/revisions\/4882"}],"up":[{"embeddable":true,"href":"https:\/\/www.vanderbilt.edu\/csb\/wp-json\/wp\/v2\/pages\/120"}],"wp:attachment":[{"href":"https:\/\/www.vanderbilt.edu\/csb\/wp-json\/wp\/v2\/media?parent=1548"}],"wp:term":[{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.vanderbilt.edu\/csb\/wp-json\/wp\/v2\/tags?post=1548"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}