  {"id":5143,"date":"2024-02-21T08:19:06","date_gmt":"2024-02-21T14:19:06","guid":{"rendered":"https:\/\/www.vanderbilt.edu\/csb\/?p=5143"},"modified":"2024-02-21T08:19:06","modified_gmt":"2024-02-21T14:19:06","slug":"csb-core-update","status":"publish","type":"post","link":"https:\/\/www.vanderbilt.edu\/csb\/2024\/02\/21\/csb-core-update\/","title":{"rendered":"CSB Core Update"},"content":{"rendered":"<p><img data-attachment-id=\"5146\" data-permalink=\"https:\/\/www.vanderbilt.edu\/csb\/2024\/02\/21\/csb-core-update\/coreupdategraphic\/\" data-orig-file=\"https:\/\/cdn.vanderbilt.edu\/vu-URL\/wp-content\/uploads\/sites\/212\/2024\/02\/21081220\/CoreUpdateGraphic.png\" data-orig-size=\"1640,924\" data-comments-opened=\"1\" data-image-meta=\"{&quot;aperture&quot;:&quot;0&quot;,&quot;credit&quot;:&quot;&quot;,&quot;camera&quot;:&quot;&quot;,&quot;caption&quot;:&quot;&quot;,&quot;created_timestamp&quot;:&quot;0&quot;,&quot;copyright&quot;:&quot;&quot;,&quot;focal_length&quot;:&quot;0&quot;,&quot;iso&quot;:&quot;0&quot;,&quot;shutter_speed&quot;:&quot;0&quot;,&quot;title&quot;:&quot;&quot;,&quot;orientation&quot;:&quot;0&quot;}\" data-image-title=\"CoreUpdateGraphic\" data-image-description=\"\" data-image-caption=\"\" data-medium-file=\"https:\/\/cdn.vanderbilt.edu\/vu-URL\/wp-content\/uploads\/sites\/212\/2024\/02\/21081220\/CoreUpdateGraphic-300x169.png\" data-large-file=\"https:\/\/cdn.vanderbilt.edu\/vu-URL\/wp-content\/uploads\/sites\/212\/2024\/02\/21081220\/CoreUpdateGraphic-1024x577.png\" loading=\"lazy\" class=\"alignleft wp-image-5146 size-medium\" src=\"https:\/\/cdn.vanderbilt.edu\/vu-URL\/wp-content\/uploads\/sites\/212\/2024\/02\/21081220\/CoreUpdateGraphic-300x169.png\" alt=\"\" width=\"300\" height=\"169\" srcset=\"https:\/\/cdn.vanderbilt.edu\/vu-URL\/wp-content\/uploads\/sites\/212\/2024\/02\/21081220\/CoreUpdateGraphic-300x169.png 300w, https:\/\/cdn.vanderbilt.edu\/vu-URL\/wp-content\/uploads\/sites\/212\/2024\/02\/21081220\/CoreUpdateGraphic-1024x577.png 1024w, https:\/\/cdn.vanderbilt.edu\/vu-URL\/wp-content\/uploads\/sites\/212\/2024\/02\/21081220\/CoreUpdateGraphic-768x433.png 768w, https:\/\/cdn.vanderbilt.edu\/vu-URL\/wp-content\/uploads\/sites\/212\/2024\/02\/21081220\/CoreUpdateGraphic-1536x865.png 1536w, https:\/\/cdn.vanderbilt.edu\/vu-URL\/wp-content\/uploads\/sites\/212\/2024\/02\/21081220\/CoreUpdateGraphic.png 1640w\" sizes=\"(max-width: 300px) 100vw, 300px\" \/>The Biophysical Instrumentation Core and the Megalab Core have been combined to form the new <strong><em>Vanderbilt Center for Structural Biology Labs and Instrumentation Facility<\/em><\/strong>.<\/p>\n<p>The facility supports mass photometry, biolayer interferometry, stopped-flow spectrometry, microscale thermophoresis, dynamic light scattering, circular dichroism and microcalorimetry instruments for measuring macromolecular conformation, stability and binding interactions. The facility also provides expression vectors\/strains and technical expertise to assist researchers with large-scale production of recombinant proteins in <em>E. coli<\/em>.<a href=\"https:\/\/cdn.vanderbilt.edu\/vu-URL\/wp-content\/uploads\/sites\/212\/2024\/02\/21080725\/CSB-Biophysical-Core_Feb2024-pricing.png\"><img data-attachment-id=\"5145\" data-permalink=\"https:\/\/www.vanderbilt.edu\/csb\/2024\/02\/21\/csb-core-update\/csb-biophysical-core_feb2024-pricing\/\" data-orig-file=\"https:\/\/cdn.vanderbilt.edu\/vu-URL\/wp-content\/uploads\/sites\/212\/2024\/02\/21080725\/CSB-Biophysical-Core_Feb2024-pricing.png\" data-orig-size=\"951,535\" data-comments-opened=\"1\" data-image-meta=\"{&quot;aperture&quot;:&quot;0&quot;,&quot;credit&quot;:&quot;&quot;,&quot;camera&quot;:&quot;&quot;,&quot;caption&quot;:&quot;&quot;,&quot;created_timestamp&quot;:&quot;0&quot;,&quot;copyright&quot;:&quot;&quot;,&quot;focal_length&quot;:&quot;0&quot;,&quot;iso&quot;:&quot;0&quot;,&quot;shutter_speed&quot;:&quot;0&quot;,&quot;title&quot;:&quot;&quot;,&quot;orientation&quot;:&quot;0&quot;}\" data-image-title=\"CSB-Biophysical-Core_Feb2024-pricing\" data-image-description=\"\" data-image-caption=\"\" data-medium-file=\"https:\/\/cdn.vanderbilt.edu\/vu-URL\/wp-content\/uploads\/sites\/212\/2024\/02\/21080725\/CSB-Biophysical-Core_Feb2024-pricing-300x169.png\" data-large-file=\"https:\/\/cdn.vanderbilt.edu\/vu-URL\/wp-content\/uploads\/sites\/212\/2024\/02\/21080725\/CSB-Biophysical-Core_Feb2024-pricing.png\" loading=\"lazy\" class=\"alignright wp-image-5145\" src=\"https:\/\/cdn.vanderbilt.edu\/vu-URL\/wp-content\/uploads\/sites\/212\/2024\/02\/21080725\/CSB-Biophysical-Core_Feb2024-pricing.png\" alt=\"\" width=\"520\" height=\"293\" srcset=\"https:\/\/cdn.vanderbilt.edu\/vu-URL\/wp-content\/uploads\/sites\/212\/2024\/02\/21080725\/CSB-Biophysical-Core_Feb2024-pricing.png 951w, https:\/\/cdn.vanderbilt.edu\/vu-URL\/wp-content\/uploads\/sites\/212\/2024\/02\/21080725\/CSB-Biophysical-Core_Feb2024-pricing-300x169.png 300w, https:\/\/cdn.vanderbilt.edu\/vu-URL\/wp-content\/uploads\/sites\/212\/2024\/02\/21080725\/CSB-Biophysical-Core_Feb2024-pricing-768x432.png 768w\" sizes=\"(max-width: 520px) 100vw, 520px\" \/><\/a><\/p>\n<p>With the new name comes updated usage rates. The various instruments are separated into a tiered pricing structure. Click on the image to the right to see the rates.<\/p>\n<p><img data-attachment-id=\"5144\" data-permalink=\"https:\/\/www.vanderbilt.edu\/csb\/2024\/02\/21\/csb-core-update\/saracho-kroh-3\/\" data-orig-file=\"https:\/\/cdn.vanderbilt.edu\/vu-URL\/wp-content\/uploads\/sites\/212\/2024\/02\/21080630\/Saracho-Kroh-3.png\" data-orig-size=\"329,748\" data-comments-opened=\"1\" data-image-meta=\"{&quot;aperture&quot;:&quot;0&quot;,&quot;credit&quot;:&quot;&quot;,&quot;camera&quot;:&quot;&quot;,&quot;caption&quot;:&quot;&quot;,&quot;created_timestamp&quot;:&quot;0&quot;,&quot;copyright&quot;:&quot;&quot;,&quot;focal_length&quot;:&quot;0&quot;,&quot;iso&quot;:&quot;0&quot;,&quot;shutter_speed&quot;:&quot;0&quot;,&quot;title&quot;:&quot;&quot;,&quot;orientation&quot;:&quot;0&quot;}\" data-image-title=\"Saracho-Kroh-3\" data-image-description=\"\" data-image-caption=\"\" data-medium-file=\"https:\/\/cdn.vanderbilt.edu\/vu-URL\/wp-content\/uploads\/sites\/212\/2024\/02\/21080630\/Saracho-Kroh-3-132x300.png\" data-large-file=\"https:\/\/cdn.vanderbilt.edu\/vu-URL\/wp-content\/uploads\/sites\/212\/2024\/02\/21080630\/Saracho-Kroh-3.png\" loading=\"lazy\" class=\"alignleft wp-image-5144\" src=\"https:\/\/cdn.vanderbilt.edu\/vu-URL\/wp-content\/uploads\/sites\/212\/2024\/02\/21080630\/Saracho-Kroh-3.png\" alt=\"\" width=\"100\" height=\"227\" srcset=\"https:\/\/cdn.vanderbilt.edu\/vu-URL\/wp-content\/uploads\/sites\/212\/2024\/02\/21080630\/Saracho-Kroh-3.png 329w, https:\/\/cdn.vanderbilt.edu\/vu-URL\/wp-content\/uploads\/sites\/212\/2024\/02\/21080630\/Saracho-Kroh-3-132x300.png 132w\" sizes=\"(max-width: 100px) 100vw, 100px\" \/>VU and VUMC researchers receive one-on-one instrument training so that they will be able to perform their experiments independently. <a href=\"mailto:noah.saracho@vanderbilt.edu\">Email Noah Saracho<\/a> to set up core access and to schedule training. <a href=\"mailto:heather.k.kroh@vumc.org\">Email Facility Director Heather Kroh<\/a> to schedule a consultation to discuss experimental strategies or to provide advice on specific research projects.<\/p>\n<p>&nbsp;<\/p>\n","protected":false},"excerpt":{"rendered":"<p>The Biophysical Instrumentation Core and the Megalab Core have been combined to form the new Vanderbilt Center for Structural Biology Labs and Instrumentation Facility. The facility supports mass photometry, biolayer interferometry, stopped-flow spectrometry, microscale thermophoresis, dynamic light scattering, circular dichroism and microcalorimetry instruments for measuring macromolecular conformation, stability and binding interactions. The facility also provides&#8230;<\/p>\n","protected":false},"author":1185,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"spay_email":"","jetpack_publicize_message":"","jetpack_is_tweetstorm":false,"jetpack_publicize_feature_enabled":true},"categories":[1],"tags":[],"acf":[],"jetpack_featured_media_url":"","jetpack_publicize_connections":[],"jetpack_sharing_enabled":true,"_links":{"self":[{"href":"https:\/\/www.vanderbilt.edu\/csb\/wp-json\/wp\/v2\/posts\/5143"}],"collection":[{"href":"https:\/\/www.vanderbilt.edu\/csb\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.vanderbilt.edu\/csb\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.vanderbilt.edu\/csb\/wp-json\/wp\/v2\/users\/1185"}],"replies":[{"embeddable":true,"href":"https:\/\/www.vanderbilt.edu\/csb\/wp-json\/wp\/v2\/comments?post=5143"}],"version-history":[{"count":12,"href":"https:\/\/www.vanderbilt.edu\/csb\/wp-json\/wp\/v2\/posts\/5143\/revisions"}],"predecessor-version":[{"id":5158,"href":"https:\/\/www.vanderbilt.edu\/csb\/wp-json\/wp\/v2\/posts\/5143\/revisions\/5158"}],"wp:attachment":[{"href":"https:\/\/www.vanderbilt.edu\/csb\/wp-json\/wp\/v2\/media?parent=5143"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.vanderbilt.edu\/csb\/wp-json\/wp\/v2\/categories?post=5143"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.vanderbilt.edu\/csb\/wp-json\/wp\/v2\/tags?post=5143"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}